Interleague play is introduced for the first time as part of the regular season. Ken Griffey, Jr. wins the AL MVP, hitting 56 home runs. The Florida Marlins become the first wild card team to win a World Series, defeating the Cleveland Indians in Game 7 on a walk-off bases-loaded single by Édgar Rentería.

• Tony Gwynn
• David Cone
• Manny Ramírez